Bioreduction of α-haloacetophenones by Rhodotorula glutinis and Geotrichum candidum
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Chiral Pharmaceutical Intermediaries Obtained by Reduction of 2-Halo-1-(4-substituted phenyl)-ethanones Mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182
Enantioselective reductions of p-R(1)-C(6)H(4)C(O)CH(2)R(2) (R(1) = Cl, Br, CH(3), OCH(3), NO(2) and R(2) = Br, Cl) mediated by Geotrichum candidum CCT 1205 and Rhodotorula glutinis CCT 2182 afforded the corresponding halohydrins with complementary R and S configurations, respectively, in excellent yield and enantiomeric excesses. The obtained (R)- or (S)-halohydrins are important building bloc...
متن کاملDisseminated Geotrichum candidum infection.
The pathogenicity of the fungus Geotrichum candidum in humans has not been clearly defined. A patient with acute leukemia who developed a fatal disseminated G. candidum infection while neutropenic is described. At autopsy examination, this patient was misdiagnosed on the basis of histopathology as having disseminated candidiasis until G. candidum was isolated from postmortem culture specimens. ...
متن کاملClinical bovine mastitis caused by Geotrichum candidum
Mastitis, which has multiple and complex aetiology, is a common syndrome among bovines and inflicts enormous losses on livestock owners. The mastitis cases are infectious in nature and are usually caused by bacteria, fungi/yeasts and some algae. An interesting case of protracted clinical mastitis in a Holstein-Fresian cow in its third lactation was encountered, with exclusive involvement of Geo...
متن کاملElectron microscopy of Rhodotorula glutinis.
Thyagarajan, T. R. (Dartmouth Medical School, Hanover, N. H.), S. F. Conti, and H. B. Naylor. Electron microscopy of Rhodotorula glutinis. J. Bacteriol. 83:381-394. 1962.-The structure and manner of nuclear division in Rhodotorula glutinis was studied by electron microscopy of ultrathin sections. Parallel studies with the light microscope, employing conventional staining techniques and phase-co...
متن کاملLipolytic fermentations of stickwater by Geotrichum candidum and Candida lipolytica.
Stickwater, a by-product of the fish meal and oil industry, is an aqueous suspension of fish proteins, lipids, and other materials, and also contains soluble nonprotein nitrogen but not carbohydrate. It is usually partially evaporated by heat to a marketable form called "fish solubles," which is sold with an acid preservative as an animal feed supplement. However, fish solubles are only used to...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2003
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0004.a38